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October 2020

Sickle cell anemia
Sickle cell anemia Types of adult hemoglobin  Hb A1 = 97% of adult hemoglobin, composed of 2 α and 2 β chains (α2β2).  Hemoglobin (Hb A2) = ...
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Case study (30) – Plasmodium falciparum Malaria
Case study (30) – Plasmodium falciparum Malaria  Questions:  Q1. What abnormality is seen in the peripheral blood film?     Q2. What are t...
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Pyruvate Kinase Deficiency
Pyruvate Kinase Deficiency - Infrequent genetic metabolic disease caused by a deficiency of pyruvate kinase enzyme, characterized by variabl...
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 Case study (29) – Acute Promyelocytic Leukemia (PML)
Case study (29) – Acute Promyelocytic Leukemia (PML)   A 36-year-old woman has a history of fatigue for 1 week.  Her menstrual period has la...
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Hereditary elliptocytosis (HE)
Hereditary elliptocytosis (HE) - Hereditary Elliptocytosis, or ovalocytosis, is an inherited blood disease in which the RBC is oval rather t...
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Case study (28) – Immune Thrombocytopenic Purpura
Case study (28) – Immune Thrombocytopenic Purpura   A 4-year-old child has a history of bruising on the face, neck, and lower limbs for 3 to...
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Glucose-6-Phosphate Dehydrogenase Deficiency (G6PDD)
Glucose-6-Phosphate Dehydrogenase Deficiency (G6PDD)   - G6PD is a metabolic enzyme required in the pentose phosphate pathway and is particu...
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