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Case Study (11)- Chronic myeloid leukemia currently in remission

Case Study (11)- Chronic myeloid leukemia currently in remission

Case Study (11)- Chronic myeloid leukemia currently in remission  

History: 

A 45-year-old woman was diagnosed with chronic myeloid leukemia (CML) 1 year ago. The patient is regularly treated with a chemotherapeutic regime as a protocol. 

Laboratory Investigations: 

1. CBC: 

RBC:3.49 X 106/μL (4-5.5 X 106/μL) 

HGB: 107 g/dL (120-174 g/dL) 

HCT: 38 % (36-52%)
MCV: 108.6 fL (76–96 fL)
MCH: 30.5 pg (27-32 pg)
MCHC: 281 g/L (300-350 g/L) 

RDWsd:83.1 fL (20-42 fL) 

RDWcv: --- % (0-16 %) 

WBC: 33.20 X103/ μL (5–10 X 103/ μL) 

Neutrophils: 23.97 X 103/μL (2-7.5 X 103/μL) 

Lymphocytes: 2.46 X 103/μL (1.08–3.17 X 103/μL) 

Monocytes: 2.29 X 103/μL (0.15-0.7 X 103/μL) 

Eosinophils: 1.53 X 103/μL (0-0.5 X 103/μL) 

Basophils: 2.95 X 103/μL (0-0.15 X 103/μL) 

Neutrophils %: 72.2 % (40-75 %) 

Lymphocytes %: 7.4 % (14.76-45.4 %)
Monocytes %: 6.9 % (3-7 %)
Eosinophils %: 4.6 % (0-5 %) 

Basophils %: 8.9 % (0-1.5 %) 

PLT: --- X 103/μL (150-400 X 103/μL) 

Result from the 2-fold diluted sample (with saline) 

RBC:1.81 X 106/μL (4-5.5 X 106/μL) 

HGB: 52 g/dL (120-174 g/dL) 

HCT: 19.2 % (36-52%)
MCV: 106.2 fL (76–96 fL)
MCH: 28.5 pg (27-32 pg)
MCHC: 269 g/L (300-350 g/L) 

RDWsd: 76.5.1 fL (20-42 fL) 

RDWcv: --- % (0-16 %) 

WBC: 12.34 X103/ μL (5–10 X 103/ μL) 

Neutrophils: 9.63 X 103/μL (2-7.5 X 103/μL) 

Lymphocytes: 0.86 X 103/μL (1.08–3.17 X 103/μL) 

Monocytes: 0.93 X 103/μL (0.15-0.7 X 103/μL) 

Eosinophils: 0.58 X 103/μL (0-0.5 X 103/μL) 

Basophils: 0.35 X 103/μL (0-0.15 X 103/μL) 

Neutrophils %: 78 % (40-75 %) 

Lymphocytes %: 7 % (14.76-45.4 %)
Monocytes %: 7.5 % (3-7 %)
Eosinophils %: 4.7 % (0-5 %) 

Basophils %: 2.8 % (0-1.5 %) 

PLT: 905 X 103/μL (150-400 X 103/μL) 

Peripheral blood smear 

2. Bone marrow examination: 

3. Other laboratory findings 

- Other laboratory findings are not remarkable. 

Diagnosis 

Chronic myeloid leukemia currently in remission  

Disease course 

- The patient is registered for the stem cell transplantation waiting list.
- An HLA-identical bone marrow donor is searched for. 















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