A 62-year-old diabetic man was subjected to left lower limb amputation. One day after the surgical operation he developed a general sickness and low-grade fever (38.3 °C). 

RBC:2.95 X 106/μL (4-5.5 X 106/μL) 

HGB: 95 g/dL (120-174 g/dL) 

HCT: 30.7% (36-52%)

MCV: 103.8 fL (76–96 fL)

MCH: 32.2 pg (27-32 pg)

MCHC: 310 g/L (300-350 g/L) 

RDWsd:56.8 fL (20-42 fL) 

RDWcv: 14.9% (0-16 %) 

WBC: 24.76 X103/ μL (5–10 X 103/ μL) 

Neutrophils: 22.04 X 103/μL (2-7.5 X 103/μL) 

Lymphocytes: 1.54 X 103/μL (1.08–3.17 X 103/μL) 

Monocytes: 1.06 X 103/μL (0.15-0.7 X 103/μL) 

Eosinophils: 0.1 X 103/μL (0-0.5 X 103/μL) 

Basophils: 0.02 X 103/μL (0-0.15 X 103/μL) 

Neutrophils %: 89 % (40-75 %) 

Lymphocytes %: 6.2 % (14.76-45.4 %)

Monocytes %: 4.3 % (3-7 %)

Eosinophils %: 0.4 % (0-5 %) 

Basophils %: 0.1 % (0-1.5 %) 

PLT: 76 X 103/μL (150-400 X 103/μL) 

- CRP (82 [ <5] mg/L) 

- Pro-calcitonin levels (4 [<0.5]ng/ mL). 

- The INR value is 2.8 [0.9-1.15]. 

- Liver and renal function tests (including transaminases, alkaline phosphatase, lactic dehydrogenase, blood urea nitrogen, and creatinine levels) are suggestive of the development of multi-organ failure. 

- Blood culture was not obtained (the patient was already given antibiotics). The patient then developed bruises. 

Sepsis with severe anemia and thrombocytopenia. 

- Platelet concentrates and packed RBCs were transfused. 

- Two days after the initiation of antibiotic therapy the patient’s general status dramatically improved.

- Within ten days the CBC count tended to return to the normal range and the other biochemical parameters also normalized.