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Case study (14)- Eosinophilia in carcinoid syndrome

Case study (14)- Eosinophilia in carcinoid syndrome 

History: 

A 65-year-old woman was subjected to surgery to remove multiple metastases of a gastrointestinal tumor. 

Laboratory Investigations: 

1. CBC: 

RBC:4.04 X 106/μL (4-5.5 X 106/μL) 

HGB:120 g/dL (120-174 g/dL) 

HCT: 37.9 % (36-52%)
MCV: 94.1 fL (76–96 fL)
MCH: 29.8 pg (27-32 pg)
MCHC: 317 g/L (300-350 g/L) 

RDWsd:37.4 fL (20-42 fL) 

RDWcv: 13.3 % (0-16 %) 

WBC: 5.04 X103/ μL (5–10 X 103/ μL) 

Neutrophils: 2.34 X 103/μL (2-7.5 X 103/μL) 

Lymphocytes: 1.13 X 103/μL (1.08–3.17 X 103/μL) 

Monocytes: 0.51 X 103/μL (0.15-0.7 X 103/μL) 

Eosinophils: 0.98 X 103/μL (0-0.5 X 103/μL) 

Basophils: 0.07 X 103/μL (0-0.15 X 103/μL) 

Neutrophils %: 46.6 % (40-75 %) 

Lymphocytes %: 22.5 % (14.76-45.4 %)
Monocytes %: 10.1 % (3-7 %)
Eosinophils %: 19.5 % (0-5 %) 

Basophils %: 1.3 % (0-1.5 %) 

PLT: 233 X 103/μL (150-400 X 103/μL) 

Peripheral blood smear 

2. Other laboratory findings 

- Serum levels of chromogranin A, the marker of carcinoid tumors markedly exceeded the upper limit of normal. 

Diagnosis 

Eosinophilia in carcinoid syndrome 

Disease course 

- Chromogranin A levels dropped dramatically after the surgery. One month later the eosinophil count was in the normal range. 



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