Case study (12)- Transient thrombocytosis due to unknown origin with macrocytic hypochromic anemia.
History:
A 35-year-old man was diagnosed with schizophrenia 10 years ago. He is also a known drug user.
He suffered multiple traumas in an accident.
Laboratory Investigations:
1. CBC:
RBC:3.48 X 106/μL (4-5.5 X 106/μL)
HGB: 100 g/dL (120-174 g/dL)
HCT: 33.7 % (36-52%)
MCV: 96.9 fL (76–96 fL)
MCH: 28.7 pg (27-32 pg)
MCHC: 296 g/L (300-350 g/L)
RDWsd:55.2 fL (20-42 fL)
RDWcv: 17.4 % (0-16 %)
WBC: 13.08 X103/ μL (5–10 X 103/ μL)
Neutrophils: 9.78 X 103/μL (2-7.5 X 103/μL)
Lymphocytes: 2.04 X 103/μL (1.08–3.17 X 103/μL)
Monocytes: 0.86 X 103/μL (0.15-0.7 X 103/μL)
Eosinophils: 0.31 X 103/μL (0-0.5 X 103/μL)
Basophils: 0.08 X 103/μL (0-0.15 X 103/μL)
Neutrophils %: 74.8 % (40-75 %)
Lymphocytes %: 15.6 % (14.76-45.4 %)
Monocytes %: 6.6 % (3-7 %)
Eosinophils %: 2.4 % (0-5 %)
Basophils %: 0.6 % (0-1.5 %)
PLT: 897 X 103/μL (150-400 X 103/μL)
Peripheral blood smear
2. Other laboratory findings
- Other routine clinical laboratory results are consistent with systemic cell damage (with increased lactic dehydrogenase and creatine kinase values) and impaired hepatic function (high transaminase activities).
- CRP levels were elevated (47 mg/L [ref value: <5 mg/L]).
Diagnosis
Transient thrombocytosis due to unknown origin with macrocytic hypochromic anemia.
Disease course
- Multiple surgical procedures were performed to stabilize the patient’s status. Efforts were made to maintain drug abstinence. Antipsychotic therapy was adjusted.
- Transient thrombocytosis due to unknown origin with macrocytic hypochromic anemia. History: A 35-year-old man was diagnos…){kind=link}
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